Themmila Khamrang

Coordination geometry-induced optical imaging of L-cysteine in cancer cells using imidazopyridine-based copper(II) complexes Selvarasu Priyanga,a Themmila Khamrang,b Marappan Velusamy,b Sellamuthu Karthi,c Balasubramaniem Ashokkumarc and Ramasamy Mayilmurugan*a Author affiliations * Corresponding authors a Bioinorganic Chemistry Laboratory/Physical Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, India E-mail: mayilmurugan.chem@mkuniversity.org b Department of Chemistry,...

Coordination Geometry Induced Optical Imaging of L-Cysteine in Cancer Cells using Imidazopyridine-Based Copper(II) Complexes Priyanga Selvarasu, Themmila Khamrang, Marappan Velusamy, Sellamuthu Karthi, Balasubramaniem Ashokkumar  and Mayilmurugan Ramasamy Abstract The overexpression of cysteine cathepsins proteases is known in a wide variety of cancers, which enhances L-cysteine concentration in tumor cells.

New copper(II) complexes [Cu(L1)2(H2O)](ClO4)2, 1 [L1 = 2-pyridin-2-yl-quinoline], [Cu(L2)2(H2O)](ClO4)2, 2 [L2 = 2-pyridin-2-yl-quinoxaline], [Cu(L3)2(H2O)](ClO4)2, 3 [L3 = 6,7-dimethyl-2-pyridin-2-yl-quinoxaline], [Cu(L4)2(H2O)](ClO4)2, 4 [L4 = 4-phenyl-2-pyridin-2-yl-quinoline] and [Cu(L5)2(H2O)](ClO4)2, 5 [L5 = 4-phenyl-2-pyridin-2-yl-quinazoline] were synthesized and characterized as the catalysts for selective fixation of atmospheric CO2.