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Thirupathi Reddy Mokalla on Muck Rack

Thirupathi Reddy Mokalla

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Concerns with the statistical analysis in “Effect of combined GLP-1 analogue and bupropion/naltrexone on weight loss: a retrospective cohort study”

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By Henry Robertson, Sherri L Pals, David Allison, Thirupathi Reddy Mokalla
| Nature Verified
To the Editor: Naude et al. [1] evaluated whether there were additive effects of prescribing bupropion/naltrexone on top of a glucagon-like peptide 1 (GLP-1) analogue as weight loss therapy. GLP-1 analogues are known to be an effective treatment for weight loss, and the authors stated based on their analysis that the addition of bupropion/naltrexone was associated with greater weight loss, including in patients who were initially non-responsive to GLP-1 analogues.
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