INTRODUCTION Knee osteoarthritis (OA) is the most common reason for knee pain in adults and is associated with increasing prevalence of comorbidities (such as obesity), physical inactivity,1 and increased risk for cardiovascular disease and death.2, 3 Exercise therapy is a cornerstone in clinical care to reduce knee OA–related pain.4-6 The current exercise recommendation for adults with chronic diseases and disabilities is 150 min/wk of moderate- to vigorous-intensity aerobic exercise.7 The...