Thomas Colson on Muck Rack

Thomas Colson

  • Editorial Account Manager and Writer, The Content Engine
London
As seen in: MSN, MSN Australia, MSN Canada, Business Insider, Business Insider Nordic, Business Insider Singapore, MSN India, MSN UK, The Independent (UK), Wiley Online Library and
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Articles

Kainate Receptor Allosteric Modulators: State of the Art and Future Directions

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By Thomas Colson, Pierre Francotte, Bernard Pirotte
| Wiley Online Library Verified
Thomas, Pirotte Bernard, Francotte Pierre, Kainate Receptor Allosteric Modulators: State of the Art and Future Directions, ChemMedChem2026, 21, e70318. Colson https://doi.org/10.1002/cmdc.70318 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data sharing not applicable to this article as no datasets were generated or analyzed during the current study.
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Exploration of the Isosteric Concept Applied to 1,2,4-Benzothiadiazine 1,1-Dioxides in the Discovery of Novel AMPA Receptor Positive Allosteric Modulators

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By Thomas Colson, Eric Goffin, Cindy Lesenfants, Pierre Fraikin
| ACS Publications
Introduction Click to copy section linkSection link copied! Glutamate is the most abundant neurotransmitter in the central nervous system (CNS) acting through the activation of ionotropic (iGluRs) and metabotropic (mGluRs) receptors. (1−4) Glutamate-dependent ionotropic receptors are composed of 4 subunits and consist in channels which are permeable to sodium and potassium ions, and to a lesser extent to calcium ions.
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Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators

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By Pierre Francotte, Yasmin Bay, Thomas Colson, Eric Goffin
| biorxiv.org
Abstract The synthesis and biological evaluation on AMPA and kainate receptors of new examples of 3,4-dihydro-2H-1,2,4-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxides is described.
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