Notes Thomas D. Norton can be contacted at . * Complete lists of the collaborators from each group are listed in the Supplementary Appendix, available at NEJM.org. Thomas D. Norton and Jorg Taubel, and Aris Baras, Gary A. Herman, and David J. Lederer, contributed equally to this letter. This letter was published on November 8, 2026, at NEJM.org. A data sharing statement provided by the authors is available with the full text of this letter at NEJM.org. Supported by Regeneron Pharmaceuticals.