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Articles by Thomas Ve
Metabolite Signature of Life's Essential 8 and Risk of Coronary Heart Disease among Low-Income Black and White Americans
This is a preprint. It has not yet been peer reviewed by a journal. The National Library of Medicine is running a pilot to include preprints that result from research funded by NIH in PMC and PubMed. Display options Abstract Background and aims: Life's Essential 8 (LE8) is a comprehensive construct of cardiovascular health. Yet, little is known about LE8 score, its metabolic correlates, and their predictive implications among Black Americans and low-income individuals.
Community-Based Interventions to Address Disparities in Cardiometabolic Diseases Among Minoritized Racial and Ethnic Groups
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Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers - Nature Communications
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Abstract The European X-ray Free Electron Laser (XFEL) and Linac Coherent Light Source (LCLS) II are extremely intense sources of X-rays capable of generating Serial Femtosecond Crystallography (SFX) data at megahertz (MHz) repetition rates. Previous work has shown that it is possible to use consecutive X-ray pulses to collect diffraction patterns from individual crystals.
By Andrew Martin, Saša Bajt, Francisco Cruz-Mazo, Alfonso M. Gañán-Calvo, Michael Christian Heymann, Matthias Frank, Romain Letrun, Andrew Morgan, Adam Round, Robin Schubert, Joachim Schulz, Carolin Seuring, Martin Trebbin, Thomas Ve, Henry Chapman, Connie Darmanin, Henry J. Kirkwood, Imrich Barák, Sadia Bari, Sandor Brockhauser, Rita Graceffa, Hans Fanghor, Bostjan Kobe, Juraj Knoška, Thomas Michelat, Jonas A. Sellberg
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Nature
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Enzyme blocker could open new treatments for neurodegenerative diseases
Researchers have uncovered how a certain molecular pathway triggers the breakdown of nerve fibers in neurodegenerative diseases – and more importantly, how to potentially switch it off. The find could lead to a new class of drugs that slows the progression of these debilitating disorders. The focus of the study was an enzyme called SARM1, which is expressed in neurons and plays a role as an immune regulator.
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