Thomke Belthle on Muck Rack

Thomke Belthle

As seen in: Wiley Online Library, ACS Publications
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Articles

Fibrin Hydrogels Reinforced by Reactive Microgels for Stimulus‐Triggered Drug Administration

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By Thomke Belthle, Hanna Malyaran, Hannah Küttner, Marc van Zandvoort
| Wiley Online Library Verified
1 Introduction Constant advances in therapeutic medicine have increased the life expectancy of the human population in recent decades. However, with an increasing life expectancy, the risk of organ damage or failure has also risen, and with it the need for tissue substitutes.
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Nanostructuring the Interior of Stimuli-Responsive Microgels by N-Vinylimidazoles Quaternized with Hydrophobic Alkyl Chains

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By Dan Demco, Andrij Pich, Thomke Belthle
| ACS Publications
The functionality of stimuli-responsive microgels can be tailor-made by manipulating their internal nanostructure induced by the chemical composition and morphology of the polymer network. Microgels with phase-separated domains on a nanoscopic length scale were synthesized by copolymerization of N-vinylcaprolactam (VCL) and amphiphilic-to-hydrophobic 1-vinyl-3-alkylimidazolium (VIM+CnH2n+1) bromides (Br–) of different alkyl chain lengths (n = 12, 14, 16) as comonomers.
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