Thorkild IA Sørensen

Confirmatory Results doi: https://doi.org/10.1101/2021.06.16.448665 Abstract Physical inactivity is associated with excess weight gain in observational studies. However, some longitudinal studies indicate reverse causality where weight gain leads to physical inactivity. As observational studies suffer from reverse causality, it is challenging to assess the true causal directions.

Abstract This study examined the relationship between body height and dementia and explored the impact of intelligence level, educational attainment, early life environment and familial factors. A total of 666,333 men, 70,608 brothers, and 7388 twin brothers born 1939–1959 and examined at the conscript board were followed in Danish nationwide registers (1969–2016). Cox regression models were applied to analyze the association between body height and dementia.

The aim was to study how, and to what degree, health-related quality of life (HRQOL), as assessed by children and their mothers, was related to overweight and obesity among children aged seven to nine years. Mother–child pairs of 149 non-overweight, 95 overweight and 16 obese children participated. We assessed HRQOL by the children’s self-report and parent proxy report module of the PedsQL™ 4.0 Generic Core Scales.