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Tianxue Han

As seen in: Royal Society of Chemistry
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Articles

Triplex formation-mediated fluorescence sensing of single bulge nucleotide-containing double-stranded RNAs by thiazole orange base surrogate-carrying PNAs

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By Yusuke Sato, Eriks Rozners, Seiichi Nishizawa, Tianxue Han
| Royal Society of Chemistry Verified
Triplex formation-mediated fluorescence sensing of single bulge nucleotide-containing double-stranded RNAs by thiazole orange base surrogate-carrying PNAs Fluorescence sensing of single bulge-containing double-stranded RNAs was achieved by triplex forming peptide nucleic acid (PNA) carrying a thiazole orange (TO) base surrogate, where the TO base surrogate facing the bulged nucleotide exhibited the light-up response through triplex formation between PNA sequence and target purine tracts in...
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