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Tim HH Coorens on Muck Rack

Tim HH Coorens

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High resolution clonal architecture of hypomutated Wilms tumours - Nature Communications

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By Henry Lee-Six, Yichen Wang, Anna Wenger, Reem Al-Saadi, Jenny Wegert, Conor Parks, Manfred Gessler, Gordan M. Vujanić, Michael Stratton, Kathy Pritchard-Jones, J. Ciaran Hutchinson, Jarno Drost, Tim HH Coorens
| Nature Verified
Abstract A paradigm of childhood cancers is that they have a low mutation burden, with some ostensibly bearing fewer mutations than the normal tissues from which they derive. We set out to resolve this paradox by examining paediatric renal cancers with exceptionally few mutations using high resolution, high depth sequencing approaches.
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