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Articles by Tim Lämmermann
Mast cell homeostasis depends on KIT ligand from dermal fibroblasts and perivascular cells in mouse skin
Keywords Tissue residency Stem cell factor Stromal cells Tissue niche Dermis Abbreviations KITLG (KIT ligand) MC (Mast cell) SCF (Stem cell factor) EC (Endothelial cell) VSMC (Vascular smooth muscle cell) MCp (Mast cell progenitor) ECM (Extracellular matrix) scRNA-seq (single cell RNA sequencing) TAM (tamoxifen) HSC (hematopoietic stem cell) CTMC (Connective tissue-type mast cell) Introduction The cell-surface receptor KIT (also known as CD117) is a type III receptor tyrosine kinase that...
Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface
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Keywords microglia microglia development microglia progenitor recruitment macrophage progenitor migration integrins immune development embryonic microglia Introduction The central nervous system (CNS) is colonized by macrophage progenitors in coordinated waves during pre- and postnatal development.1,2,3 Distinct long-lived macrophage populations in the CNS parenchyma and interfaces originate from fetal progenitors, including microglia, perivascular, intraventricular, and leptomeningeal...
By Philippe Petry, Alexander Oschwald, Simon Merkt, Thien-Ly Julia Dinh, Geoffroy Andrieux, Cylia Crisand, Hannah Botterer, Elisa Nent, Neil G. Paterson, Monique Havermans, Roman Sankowski, Oliver S. Schilling, Melanie Boerries, Lukas Amann, Olaf Groß, Andreas Schlitzer, Marco Prinz, Tim Lämmermann, Katrin Kierdorf
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Cell Press
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Macrophage network dynamics depend on haptokinesis for optimal local surveillance
Decision letter after peer review: Thank you for submitting your article "Macrophage network dynamics depend on haptokinesis for optimal local surveillance" for consideration by eLife. Your article has been reviewed by 3 peer reviewers, including Michael L Dustin as Reviewing Editor and Reviewer #1, and the evaluation has been overseen by Carla Rothlin as the Senior Editor.
T Cells: Bridge-and-Channel Commute to the White Pulp
In contrast to lymph nodes, the lymphoid regions of the spleen—the white pulp—are located deep within the organ, yielding the trafficking paths of T cells in the white pulp largely invisible. In an intravital microscopy tour de force reported in this issue of Immunity, Chauveau et al. show that T cells perform unidirectional, perivascular migration through the enigmatic marginal zone bridging channels.
Platelets, On Your Marks, Get Set, Migrate!
To use the Enhanced view of this article, please enable JavaScript on in your browser and refresh the page. PreviewPlatelets, On Your Marks, Get Set, Migrate! Sarah K. BambachxSarah K.
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