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Tin-Lap Lee

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Articles

Smad3 is essential for polarization of tumor-associated neutrophils in non-small cell lung carcinoma - Nature Communications

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By Jeff Chung Verified, Philip Chiu-Tsun Tang, Kam-Tong Leung, Chun-Kwok Wong, Tin-Lap Lee, Eric Lam Verified, Ka-Fai To, Hui-Yao Lan, Vivian Weiwen Xue
| Nature Verified
Abstract Neutrophils are dynamic with their phenotype and function shaped by the microenvironment, such as the N1 antitumor and N2 pro-tumor states within the tumor microenvironment (TME), but its regulation remains undefined. Here we examine TGF-β1/Smad3 signaling in tumor-associated neutrophils (TANs) in non-small cell lung carcinoma (NSCLC) patients. Smad3 activation in N2 TANs is negatively correlate with the N1 population and patient survival.
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Correction: Crosstalk from Non-Cancerous Mitochondria Can Inhibit Tumor Properties of Metastatic Cells by Suppressing Oncogenic Pathways

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By Benny Abraham Kaipparettu, Yewei Ma, Jun Hyoung Park, Tin-Lap Lee
| PLOS
Loading metrics Open Access Correction Benny Abraham Kaipparettu, Yewei Ma, Jun Hyoung Park, Tin-Lap Lee, Yiqun Zhang, Patricia Yotnda, Chad J. Creighton, Wai-Yee Chan, Lee-Jun C. Wong Benny Abraham Kaipparettu, Yewei Ma, Jun Hyoung Park, Tin-Lap Lee, Yiqun Zhang, Patricia Yotnda, Chad J. Creighton, Wai-Yee Chan, Lee-Jun C. Wong Published: August 22, 2019 https://doi.org/10.1371/journal.pone.0221671 Figures There are errors in Fig 1E.
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