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Aberrant bone marrow granulopoiesis generates neutrophils that promote B cell activity in neuromyelitis optica spectrum disorder
Editor’s summary Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disease of the central nervous system (CNS) driven by B cells and antibodies specific to aquaporin-4. B cells require B cell–activating factor (BAFF) to maintain their function. Here, Li et al. provide evidence that a population of neutrophils expressing interferon stimulated gene 15 (ISG15) can produce BAFF in NMOSD.
Uptake of Levilactobacillus Brevis JCM 1059 by THP-1 Cells via Interaction between SlpB and CAP-1 Promotes Cytokine Production
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