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Subtype-Specific Risk of Non-Melanoma Skin Cancers in MPN Patients: An Expanded Analysis of the MPN-K Case–Control Database
T.Barbui and A.Ghirardi, “Subtype-Specific Risk of Non-Melanoma Skin Cancers in MPN Patients: An Expanded Analysis of the MPN-K Case–Control Database,” American Journal of Hematology (2026): 1–4, https://doi.org/10.1002/ajh.70332. To the Editor, Patients with polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF) are known to have a two- to three-fold increased risk of developing non-melanoma skin cancer (NMSC) compared with the general population [1-3].
Extending the Biological Axis Linking CHIP to Cancer Emergence
To the Editor, Liu and colleagues are to be congratulated for their elegant and comprehensive study examining the prognostic impact of clonal hematopoiesis of indeterminate potential (CHIP) identified before the development of cancer [1]. Using the UK Biobank resource, they analyzed a prospective cohort of 63 486 individuals who later developed incident cancers between 2006 and 2022, of whom 2860 (4.5%) carried CHIP prior to cancer diagnosis.
A Clinically Applicable Model Using Blood Counts to Support the Diagnosis of Prefibrotic Myelofibrosis Versus Essential Thrombocythemia
Conflicts of Interest The authors declare no conflicts of interest. References 1 E. S. Jaffe, N. L. Harris, H. Stein, and J. W. Vardiman, eds., WHO Classification of Tumours: Tumours of Haematopoietic and Lymphoid Tissues (IARC Press, 2001). 2, , , et al., WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, 4th ed. (International Agency for Research on Cancer, 2008).
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