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Emicizumab in Previously Untreated Patients and Minimally Treated Patients With Hemophilia A: A Comparative Study Between Two International Cohorts
1 Introduction Hemophilia A (HA) is a rare, X-linked bleeding disorder caused by a deficiency of coagulation factor VIII (FVIII) [1]. Standard treatment for severe HA has traditionally involved prophylactic FVIII intravenous replacement therapy [2].
The Impact of Emicizumab Prophylaxis on Hospitalizations and Emergency Department Visits Among Hemophilia A Patients Is Age Related
1 Introduction Hemophilia A (HA) is a genetic disorder with an X-linked inheritance pattern, resulting from a mutation in the gene encoding coagulation factor VIII. This leads to recurrent bleeding events, primarily affecting joints and muscles [1]. Until recently, the conventional therapeutic strategy involved prophylactic intravenous infusions of factor VIII. Approximately 30% of patients develop inhibitory antibodies directed against the factor.
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