Toby N Weingarten

Abstract and Introduction Introduction Postoperative respiratory failure secondary to opioid-induced respiratory depression (hereafter termed respiratory depression) can result in permanent morbidity, such as anoxic brain injury, or even death.[1,2] In many cases, the respiratory failure seems to develop acutely and without warning, often shortly after seemingly reassuring nursing assessments.[2] Severe respiratory depression on general care units, however, is rare (3.7 to 53.3 opioid...

Risk factors for opioid-induced respiratory depression in surgical patients: a systematic review and meta-analyses Kapil Gupta1, Mahesh Nagappa2, Arun Prasad3, Lusine Abrahamyan4, Jean Wong3, Toby N Weingarten5, Frances Chung3 1 Department of Anesthesia and Pain Management, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada 2 Department of Anesthesia and Perioperative Medicine, London Health Sciences Centre and St. Joseph Health Care, Western...

Due to the absence of standardisation on the definition of postoperative pulmonary complications, some complications will not be addressed. Ventilatory variables will be measured at the critical points of the surgery, to assess the impact of surgical positioning and of the pneumoperitoneum in respiratory mechanics.