Todd Cameron
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Articles by Todd Cameron
FtsZ Forms Biomolecular Condensates in a Polar-Growing Alphaproteobacterium
Faculty, Staff and Student Publications Publication Date 4-15-2026 DOI 10.1128/mbio.00494-26 Abstract The conserved tubulin homolog FtsZ assembles into GTP-dependent protofilaments that organize the bacterial cell division machinery. Purified Escherichia coli FtsZ (FtsZEc) can form biomolecular condensates in the absence of GTP in macromolecular crowding conditions, but FtsZ condensates have not yet been confirmed in vivo.
A Predicted Helix-Turn-Helix Core Is Critical for Bacteriophage Kil Peptide to Disrupt Escherichia coli Cell Division
Open AccessArticle by Arindam Naha †, Todd A. Cameron and William Margolin William Margolin has investigated bacterial cell biology and cell division for over 30 years, the of [...] William Margolin has investigated bacterial cell biology and cell division for over 30 years, pioneering the use of GFP fusions for visualizing cell division proteins in dividing Escherichia coli cells and the use of bypass suppressors to identify cell division regulators.
Insights Into the Assembly and Regulation of the Bacterial Divisome
Abstract The ability to split one cell into two is fundamental to all life, and many bacteria can accomplish this feat several times per hour with high accuracy. Most bacteria call on an ancient homologue of tubulin, called FtsZ, to localize and organize the cell division machinery, the divisome, into a ring-like structure at the cell midpoint. The divisome includes numerous other proteins, often including an actin homologue (FtsA), that interact with each other at the cytoplasmic membrane.
Comparison of Transcriptional Profiles of Treponema pallidum During Experimental Infection of Rabbits and In Vitro Culture: Highly Similar, yet Different
Home > UTHealth > McGovern Medical School > Journal Articles > 1925 Animals, Cells, Cultured, In Vitro Techniques, Male, Rabbits, Syphilis, Transcriptome, Treponema pallidum DOWNLOADS COinS
Construction and Characterization of Functional FtsA Sandwich Fusions for Studies of FtsA Localization and Dynamics during Escherichia coli Cell Division
FtsA, a homolog of actin, is essential for cell division of Escherichia coli and is widely conserved among many bacteria. FtsA helps to tether polymers of the bacterial tubulin homolog FtsZ to the cytoplasmic membrane as part of the cytokinetic Z ring. GFP fusions to FtsA have illuminated FtsA’s localization in live E. coli, but these fusions have not been fully functional and required the presence of the native FtsA. Here, we characterize “sandwich” fusions of E.
Insights into the assembly and regulation of the bacterial divisome - Nature Reviews Microbiology
Bi, E. & Lutkenhaus, J. FtsZ ring structure associated with division in Escherichia coli. Nature 354, 161–164 (1991). Article CAS PubMed Google Scholar Yang, X. et al. GTPase activity-coupled treadmilling of the bacterial tubulin FtsZ organizes septal cell wall synthesis. Science 355, 744–747 (2017). Article CAS PubMed PubMed Central Google Scholar Bisson-Filho, A. W. et al. Treadmilling by FtsZ filaments drives peptidoglycan synthesis and bacterial cell division. Science 355, 739–743 (2017).
Things they didn’t teach you in med school
KnowCents Practice Management In their new book, the Scale My Clinic founders share some secrets to building a successful and sustainable general practice. As we write this, the world is still in the grip of the covid-19 pandemic. And while that gives us plenty of worries about what’s happening in the present, it’s also going to impact the viability of your practice in the future. Of course, you may be reading this after the pandemic has passed.
A guide to recruiting GPs
Follow these strategies to attract the best team for your clinic. If you’re a GP owner or want to start your own GP practice, there are a few skillsets that you need to master, and recruitment is one of them. Becoming proficient at recruiting GPs for your practice is critical to ensuring that you’re not stuck in long-hour work cycles where you’re doing all the heavy lifting.
A cooperative PNPase-Hfq-RNA carrier complex facilitates bacterial riboregulation
Highlights • Cryo-EM structures of PNPase in complex with the RNA chaperone Hfq and regulatory RNA • Structural insights into regulatory RNA recognition by Hfq and PNPase • Model for stabilization of regulatory RNAs and facilitation of their functions Summary Polynucleotide phosphorylase (PNPase) is an ancient exoribonuclease conserved in the course of evolution and is found in species as diverse as bacteria and humans.
Overproduction of a Dominant Mutant of the Conserved Era GTPase Inhibits Cell Division in Escherichia coli
Research Article Xiaomei Zhou, Howard K. Peters III, Xintian Li, Nina Costantino, Vandana Kumari, Genbin Shi, Chao Tu, Todd A. Cameron, Daniel P. Haeusser, Daniel E. Vega, Xinhua Ji, William Margolin, Donald L. Court Thomas J. Silhavy, Editor DOI: 10.1128/JB.00342-20 ABSTRACT Cell growth and division are coordinated, ensuring homeostasis under any given growth condition, with division occurring as cell mass doubles.
We Threw An Alien-Themed First Birthday Party For Our Son And It Was A Blast (22 Pics)
In October 2018, our family went viral when my wife gave birth to a bloody xenomorph chestburster in a local pumpkin patch. You may have even seen the story first here on Bored Panda. One year later, it was time for the little xenomorph toddler’s first Burst Day! It was so hard to believe that one whole year had gone by since our little guy burst through Nicole’s abdomen and into our hearts. Raising a xenomorph hasn’t always been an easy go.
Canadian “The Big Lebowski” Fan And Photographer Put ‘The Dude’ In Dudeoir
After struggling since childhood with body image issues, I really wanted to do something to help me to break out of my discomfort and show myself that I could love myself for who I was. And if I could do that and share a few laughs at the same time, even better. When I saw that my friend, Masika Woods from Masika May Photography was bringing Dudeoir photography into the mainstream, I knew I had to get in on the hilarity and fun.
Our Toddler Is The Star Of These 12 Christmas Cosplays
This year, instead of just decorating the house, we decided to also dress-up our one-year-old son, Jack, as 12 iconic Characters from classic Christmas movies and specials. After weeks of crafting, costuming, and photography, we think that the adorable results speak for themselves. Jack was an unwitting star of a previous viral post covered by Bored Panda, playing the baby bump in our Alien Maternity Chestburster photoshoot last Halloween. I also wrote a poem to go along with these latest photos.
Redefining the Small Regulatory RNA Transcriptome in Streptococcus pneumoniae Serotype 2 Strain D39
Meeting Presentation Dhriti Sinha, Kurt Zimmer, Todd A. Cameron, Douglas B. Rusch, Malcolm E. Winkler, Nicholas R. De Lay Victor J. DiRita, Editor DOI: 10.1128/JB.00764-18 ABSTRACT Streptococcus pneumoniae (pneumococcus) is a major human respiratory pathogen and a leading cause of bacterial pneumonia worldwide. Small regulatory RNAs (sRNAs), which often act by posttranscriptionally regulating gene expression, have been shown to be crucial for the virulence of S.
Briefly Noted
OTHERWISE ENGAGED By Lindsey Palmer C’05 (Skyhorse Publishing, 2019, $24.99.) For newly engaged New Yorkers Molly and Gabe, life is sweet—until Molly discovers that Gabe’s bestselling novel recounts a wild affair with an ex-girlfriend, who soon reappears to capitalize on the book’s success. Jealous, paranoid, and desperate, Molly spins out of control, only to be brought to her senses with the help of friends, in this smart romantic comedy that is written as a book within a book.
Redefining the sRNA Transcriptome in Streptococcus pneumoniae Serotype 2 Strain D39
Meeting Presentation Dhriti Sinha, Kurt Zimmer, Todd A. Cameron, Douglas B. Rusch, Malcolm E. Winkler, Nicholas R. De Lay DOI: 10.1128/JB.00764-18 ABSTRACT Streptococcus pneumoniae (pneumococcus) is a major human respiratory pathogen and a leading cause of bacterial pneumonia worldwide. Small regulatory RNAs (sRNAs), which often act by post-transcriptionally regulating gene expression, have been shown to be crucial for the virulence of S. pneumoniae and other bacterial pathogens.
How Interruptive Advertising Is Killing The Olympic Games
Here we are in 2016 kicking off the most-watched sporting event in the world as it returns on its four-year cycle. While no single day event can compete with two plus weeks of televised sports when it comes to overall viewership, many people don’t realize that the opening ceremony draws the largest single day audience of the games; more than 5X the audience of the Super Bowl and second only to World Cup Soccer for overall worldwide viewers.
FTC Rules of Engagement for Influencer Marketing
As digital marketing continues to evolve to include social media influencer marketing tactics, quick changes create need for regulation and oversight that is hard to keep up with. TapInfluence has written the book on influencer marketing and cracked the code on how to create programs with real influence.
The Future of FTC Regulations on Influencer Marketing Following Warner Brothers Crackdown
Influencer marketing is a creative art that relies heavily on technology and governance to sustain credibility. This translates to full and transparent disclosures. Yesterday’s news about Warner Brothers, so soon after similar news about Lord and Taylor, represents repeated failures from the perspective of the FTC to adhere to established consumer protection principles for native advertising (aka sponsored content).
Three Tips for Building Internal Support for Influencer Marketing
Influencer marketing has been around for a few years, but with the current level of media coverage and discussion around it, it is fair to say that 2016 marks its growth inflection point. No longer are marketers asking, "What's influencer marketing?" Today, many are asking, "Should we develop an influencer marketing channel?" or, "How much effort and budget should we put behind it this year?" Embracing something new, regardless of how advantageous it might be, is difficult.
Social Influencers Share Their Golden Rules Of Engagement
As more consumers grow ad-blind and impervious to other forms of digital marketing, marketers are seeking new, viable ways to connect. Influencer marketing promises to be the hero by helping brands reach their audiences through social influencers who have built a loyal and engaged following through blogs, Instagram, YouTube, Pinterest, and other channels.
4 Ways to Drive Sales With Influencer Marketing
When I think about the purchases consumers make, I often recall a book I read more than a decade ago, “Why We Buy” by Paco Underhill. The psychology of purchase behavior has always fascinated me. And it’s not just why we buy, it’s how we buy and the decisions we make along the way. As the saying goes, people love to buy but they hate to be sold. This phrase captures the essence of why we’ve seen consumers increasingly ignore and actively avoid traditional advertising.
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