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Todd Levine on Muck Rack

Todd Levine

As seen in: Wiley Online Library, Frontiers, Journal of Neurology, Neurosurgery and Psychiatry, Taylor & Francis Online, JAMA (The Journal of the American Medical Association), JAMA: Journal of the American Medical Association, HCP Live, AZ Big Media, Scottsdale Independent, Town of Paradise Valley Independent and

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Articles

The Syn-Q study: detection of cutaneous phosphorylated alpha-synuclein in Parkinson’s disease progression: a trial protocol

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By Jourdan H. Parent, Todd Levine, Roy Freeman, Christopher Gibbons
| Frontiers
Abstract Background: Parkinson’s disease (PD) is a neurodegenerative condition with progressive phosphorylated alpha-synuclein (P-SYN) deposition. Skin biopsies are a sensitive and specific source of tissue to detect intra-axonal P-SYN in patients with PD. Further, isolated REM sleep behavior disorder (iRBD) is a prodromal condition with a high risk of phenoconversion to PD.
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The Syn-sleep trial protocol: detection of cutaneous phosphorylated alpha-synuclein in REM sleep behavior disorder

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By Todd Levine, Roy Freeman, Sarrah Marcotte
| Taylor & Francis Online
ABSTRACT Background Idiopathic rapid eye movement sleep behavior disorder (iRBD) is a prodromal neurodegenerative disease of misfolded alpha-synuclein (P-SYN) with a high risk of phenoconversion to a clinically apparent synucleinopathy (including Parkinson’s disease, multiple system atrophy, or dementia with Lewy bodies) over 15 years.
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Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

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By Christopher Gibbons, Todd Levine, Charles Adler, Bailey Bellaire
| Wiley Online Library Verified
1 Introduction The neurodegenerative diseases collectively known as “synucleinopathies” include Parkinson's disease (PD), dementia with Lewy bodies (DLB), multiple system atrophy (MSA), and pure autonomic failure (PAF). Despite overlapping clinical phenotypes, the disorders are considered distinct entities with unique pathological underpinnings, but all are characterized by the deposition of phosphorylated alpha-synuclein (P-SYN) within the central and peripheral nervous systems.
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