Tomash Sergeevich Sych

Amino Acid-Stabilized Luminescent Gold Clusters for Sensing Pterin and its Analogues Pteridines are important low molecular weight biomarkers used in diagnostics of inflammation, oxidative stress, phenylketonuria, cancer, etc. In this experimental study we present a simple and selective approach to determine pteridines (pterin, leucopterin and folic acid) and nucleobase guanine concentration using luminescent gold clusters stabilized by aromatic amino acids.

Luminescent silver nanoclusters in probing immunoglobulins and serum albumins in protein mixtures The concentrations of total immunoglobulins (Ig), human serum albumin (HSA) and their relative level are important characteristics of health state. Significant increase of [Ig]/[HSA] ratio may be indicative of some blood diseases, such as multiple myeloma. We employed silver nanoclusters (AgNCs) as luminescent labels for the detection of HSA and Ig in their mixtures in a single experiment.