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Systemic inflammatory indices primarily reflect tumor burden rather than independently predict prognosis in HPV-associated oropharyngeal squamous cell carcinoma
Abstract Objectives Approximately 30% of patients with human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) have poor outcomes despite standardized treatment. Reliable biomarkers for identifying high-risk patients remain insufficiently established. To investigate the clinical significance of systemic inflammatory indices for identifying high-risk patients and to explore their associations with clinicopathological characteristics.
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