Topi Meuronen on Muck Rack

Topi Meuronen

As seen in: Nature, Atherosclerosis
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Articles

Harmonizing human plasma metabolite annotation with Plasma Benchmark - Nature Metabolism

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By Topi Meuronen, Pekka Keski-Rahkonen, Reza M. Salek, Hany Ahmed, Carl Brunius, Rikard Landberg
| Nature Verified
The human plasma metabolome has been extensively characterized: version 5.0 of the Human Metabolome Database (HMDB)1 currently encompasses 37,229 entries for metabolites reported in human blood.
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Dietary n-3 alpha-linolenic and n-6 linoleic acids modestly lower serum lipoprotein(a) concentration but differentially influence other atherogenic lipoprotein traits: A randomized trial

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By Petrus Nuotio, Maria Lankinen, Topi Meuronen, Taisa Sallinen
| Atherosclerosis Verified
Highlights • Diets enriched with either n-3 alpha-linolenic or n-6 linoleic acid decrease serum Lp(a) concentration by 7–10 %. • Alpha-linolenic acid may have more beneficial effect on other atherogenic lipoprotein traits, compared to linoleic acid. • The FADS1 rs174550 genotype does not modulate diet-induced changes in Lp(a) concentration or other lipoprotein traits. Abstract Lipoprotein(a) [Lp(a)] is a causal, genetically determined cardiovascular risk factor.
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