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Abstract Every neuron contains the same genomic information but its complement of proteins is the product of countless neuron–specific steps including pre–mRNA splicing. Despite advances in RNA sequencing techniques, pre–mRNA splicing biases that favor one isoform over another are largely inscrutable in live neurons in situ.
ABSTRACT At chemical synapses, synaptic vesicles release their acidic contents into the cleft leading to the expectation that the cleft should acidify. However, fluorescent pH probes targeted to the cleft of conventional glutamatergic synapses in both fruit flies and mice reveal cleft alkalinization, rather than acidification.
Research Articles, Cellular/Molecular Michal Stawarski, Roberto X. Hernandez, Touhid Feghhi, Jolanta A. Borycz, Zhiyuan Lu, Andrea B. Agarwal, Kelly D. Reihl, Rubens Tavora, A.W.C. Lau, Ian A. Meinertzhagen, Robert Renden and Gregory T.
Research Articles, Cellular/Molecular Michal Stawarski, Roberto X. Hernandez, Touhid Feghhi, Jolanta A. Borycz, Zhiyuan Lu, Andrea Agarwal, Kelly Reihl, Rubens Tavora, A.W.C. Lau, Ian A. Meinertzhagen, Robert Renden and Gregory T.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.