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Abstract Attention deficit hyperactivity disorder (ADHD) is a childhood-onset neurodevelopmental disorder with a large genetic component1. It affects around 5% of children and 2.5% of adults2, and is associated with several severe outcomes3,4,5,6,7,8,9,10,11. Common genetic variants associated with the disorder have been identified12,13, but the role of rare variants in ADHD is mostly unknown.
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