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As seen in: Cell Reports Medicine
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Articles

Single-cell transcriptomics of the immune system in ME/CFS at baseline and following symptom provocation

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By Elizabeth Fogarty, Paul Munn, TREx Facility, Carl J. Franconi
| Cell Reports Medicine Verified
Highlights • The ME/CFS immune system is profiled by scRNA-seq at baseline and after provocation • Monocyte dysregulation is prominent and dysregulation correlates with disease severity • Platelets are also dysregulated, but this dysregulation resolves after provocation Summary Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious and poorly understood disease.
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