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Tsung-Ying Uang

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Access to Chiral Tertiary α‐Hydroxyesters via Rhodium‐Catalyzed Enantioselective Allylation of α‐Ketoesters

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By Yu-Chu Yang, Wei-Sian Li, Ting-Shen Kuo, Tsung-Ying Uang
| Wiley Online Library Verified
Molecules containing a tertiary α-hydroxy carbonyl moiety are vital building blocks for synthesizing pharmaceuticals and natural products. In this study, we present an efficient rhodium(I)-catalyzed enantioselective allylation of α-ketoesters, providing a direct route to tertiary α-hydroxy esters.
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