Tsz Man Yau on Muck Rack

Tsz Man Yau

As seen in: Nature
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Articles

HCMV infection disrupts barrier functions and promotes epithelial–mesenchymal transition in a cholangiocyte organoid model - Nature Communications

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By Xinyan Hu, Xiaoman Zhang, Tsz Man Yau
| Nature
Abstract Human cytomegalovirus (HCMV) is associated with bile duct disorders in immunocompetent and immunocompromised individuals, including sclerosing cholangitis, biliary structures, AIDS cholangiopathy, biliary atresia (BA), and post-transplant biliary complications. Despite these clinical associations, it remains unknown whether HCMV can directly infect the bile duct epithelium and cause pathogenesis.
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