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Tueanjai Khunluck on Muck Rack

Tueanjai Khunluck

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Articles

Brusatol enhances the chemotherapy efficacy of Cisplatin and Gemcitabine in KKU-100 cholangiocarcinoma cells through ROS-mediated apoptosis

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By Ingon Inson, Chartinun Chutoe, Laddawan Senggunprai, Auemduan Prawan, Kornkamon Lertsuwan, Tueanjai Khunluck
| Nature Verified
Abstract One of the main obstacles in Cholangiocarcinoma (CCA) treatment is drug resistant to the standard therapy, Cisplatin combined with Gemcitabine (Cis/Gem). Brusatol (Bru) has shown its potential in enhancing the effects of other chemotherapeutic drugs. Therefore, this study investigates the anti-cancer effects of Bru alone or combined with chemotherapeutic drugs, Cis and Gem, in human CCA cells (KKU-100), and explores the underlying mechanisms.
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