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Articles

Whole blood transcriptomics atlas across human diseases

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By Mengzhen Li, Abdulgani Tatar, Emre Green, Cigdem Yuce Kahraman, Mustafa Ceylan, Fuat Laloğlu, Naci Ceviz, Arzu Tatar, Esra Laloğlu, Kenan Cadirci, Omer Erkan Yapca, Hilal Kiziltunc Ozmen, Turgut Yapanoğlu, Fatma ŞİMŞEK, Ayse Kevser Ozden, Pinar Tosun Tasar, Mustafa Kara, Yunus Aktas, Büşra Akpinar, Bilgehan Erkut, Mufide Nuran Akcay, Erdem Karadeniz, Esra Disci, Sabri Selcuk Atamanalp, Rifat Peksoz, Yavuz Albayrak, Atilla Eroglu, Erdal Tekin, Ali Bilal Ulaş, Ahmet Emre Paksoy, Mehmet Turgut, Ozgur Ozmen, Fatih Alper, Bulent Albayrak, Emine Cinici, Esat Aydın, Yahya Gül, Ugur Kaya, Yakup Kumtepe, Ayşenur Dostbil, Nuray Bilge, Derya Cevizli, Halil Ozcan, Bugra Kerget, Omer Araz, Fatma Tortum, Necip Altundas, Nurhak Aksungur, Salih Kara, Gurkan Ozturk, Fatma Can, Handan Alay, Ayse Albayrak, Kemalettin Özden, Ali Gur, Taner Arabaci, Serdar Saritas, Can Sevinç, Muhammed Taş, María Bueno Álvez, Fredrik Edfors, Xiangtai Kong, Xiya Song, Ozlem Altay, Bayram Yuksel, Mathias Uhlén, Saeed Shoaie, Cheng Zhang, Hasan Türkez, Adil Mardinoglu, Ebru Simsek, Gungor Akcay, Ozlem Kudas, Hakan Doneray, Atilla Cayir, Mursel Karadavut, Eyup Serhat Calik, Murat Kartal, Mehmet Ilhan Yildirgan, Yener Aydın, Mevlana Gul, Eyup Senocak, Ayse Sena Donmez, Ibrahim Kocer, Nazim Dogan, Yunus Emre Topdagi, Husnu Kursat, Ozkan Cinici, Muhammed Akif Guler, Tugba Koca Lacin, Serap Sari, Serap Kilic Kaya, Merve Ulku, Ertugrul Karatas, Mirze Muhammet Ozen, Sinan Yilar, Zulal Ozkurt, Hacer Akgul Ceyhun, Mehmet Akif Sirin, Gulden Sincan, Momen Kanjee, Busra Saruhan, Sumeyye Ozturk Eren, Bahadir Utlu, Esra Tanriverdi
| Nature Verified
Abstract We present a WBT Atlas, comprising 4444 WBT samples across 98 distinct health conditions, enabling systematic exploration of disease-associated transcriptomic signatures. Health condition–specific profiles are characterized across immune, metabolic, and cell-type specific features at the gene, gene module, and pathway levels.
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