Tuncer Onay on Muck Rack

Tuncer Onay

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Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development

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By Feinberg Cardiovascular, Shintaro Ide, Yoshiro Maezawa, Tuncer Onay
| ASN Journals
Figure][1] Background The mammalian kidney develops through reciprocal inductive signals between the metanephric mesenchyme and ureteric bud. Transcription factor 21 (Tcf21) is highly expressed in the metanephric mesenchyme, including Six2-expressing cap mesenchyme and Foxd1-expressing stromal mesenchyme. Tcf21 knockout mice die in the perinatal period from severe renal hypodysplasia.
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