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Tung-Ying Hung

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Dipeptidyl Peptidase‐4 Inhibitors and Risk of Heart Failure in Patients With Type 2 Diabetes Mellitus and End‐Stage Renal Disease Requiring Dialysis

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By Tzu-Han Lin, Liang-Yu Lin, Tzu-Chieh Lin, Tung-Ying Hung
| Wiley Online Library Verified
Introduction Evidence on the safety of antidiabetic agents in end-stage renal disease (ESRD) patients requiring dialysis, a group often excluded from randomized controlled trials, is scant. Dipeptidyl peptidase-4 inhibitors (DPP-4i), widely used for type 2 diabetes mellitus (T2DM) management in this group, have raised concerns regarding the risk of heart failure (HF). However, real-world evidence on HF risk with DPP-4i in dialysis-dependent diabetic patients is limited.
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