Tushabe John Vianney on Muck Rack

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Extensive transmission and variation in a functional receptor for praziquantel resistance in endemic Schistosoma mansoni

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By Duncan J Berger, Sang-Kyu Park, Thomas Crellen, Tushabe John Vianney
| biorxiv.org
Abstract Mass-drug administration (MDA) of human populations using praziquantel monotherapy has become the primary strategy for controlling and potentially eliminating the major neglected tropical disease schistosomiasis. To understand how long-term MDA impacts schistosome populations, we analysed whole-genome sequence data of 570 Schistosoma mansoni samples (and the closely related outgroup species, S.
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