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Tzu-Ying Sung on Muck Rack

Tzu-Ying Sung

As seen in: Taylor & Francis Online
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Articles

Investigation of Ca2+ signaling induced by the flavonoid diosmin in glioblastoma cells and its potential implications in the treatment using the Ca2+ chelating agent BAPTA-AM

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By Yen-Hui Lin, Lyh-Jyh Hao, Chiang-Ting Chou, Tzu-Ying Sung
| Taylor & Francis Online
Abstract Flavonoids, found in fruits and vegetables, can potentially prevent brain diseases. Diosmin (diosmetin-7-O-rutinoside), a flavonoid, exhibits various pharmacological activities, but its impact on calcium ion (Ca2+) signaling and the associated mechanisms in human glioblastoma cells remain unclear. This study investigated the effect of diosmin on intracellular Ca2+ levels ([Ca2+]i), cell viability, and the participation of Ca2+-related pathways in DBTRG-05MG human glioblastoma cells.
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