Ubaldina Galli on Muck Rack

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Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy

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By Marianna Moro, Ubaldina Galli, Federica Carolina Balestrero
| dx.doi.org
Introduction Click to copy section linkSection link copied! Moonlighting proteins exhibit multiple functions beyond their canonical enzymatic activity, often switching roles depending on cellular conditions or localizing to different subcellular compartments to perform different tasks. Extensive research has highlighted their critical involvement in cancer development and progression, making them attractive targets for drug discovery.
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