Umaimainthan Palendira on Muck Rack

Umaimainthan Palendira

As seen in: Nature, Wiley Online Library, MDPI
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Articles

Stroma-infiltrating T cell spatiotypes define immunotherapy outcomes in adolescent and young adult patients with melanoma - Nature Communications

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By Xinyu Bai, Peter Ferguson, Ismael A. Vergara, Umaimainthan Palendira, Georgina V. Long, Richard A. Scolyer, Grace H. Attrill
| Nature Verified
Abstract The biological underpinnings of therapeutic resistance to immune checkpoint inhibitors (ICI) in adolescent and young adult (AYA) melanoma patients are incompletely understood. Here, we characterize the immunogenomic profile and spatial architecture of the tumor microenvironment (TME) in AYA (aged ≤ 30 years) and older adult (aged 31–84 years) patients with melanoma, to determine the AYA-specific features associated with ICI treatment outcomes.
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Vaccines | Free Full-Text | CXCR3 Provides a Competitive Advantage for Retention of M. tuberculosis-Specific Tissue-Resident Memory T Cells following a Mucosal Tuberculosis Vaccine

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By Diana Quan, Manuela Flórido, Umaimainthan Palendira, Ellis Armitage
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
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Epstein-Barr virus and multiple sclerosis: moving from questions of association to questions of mechanism

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By Olivia Thomas, Alan Rickinson, Umaimainthan Palendira
| Wiley Online Library Verified
Introduction Epstein–Barr virus (EBV) is arguably one of the most successful pathogens to infect humans. Over 90% people in all countries naturally acquire the virus, often in their first decade, and will thereafter carry EBV for life as a latent, usually asymptomatic, infection. However, this seemingly innocuous agent has a much more sinister side to its character.
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