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Articles

Short-term risk of falls among initiators of controlled-release tapentadol versus oxycodone in New South Wales between 2014 and 2020: A population-based retrospective cohort study

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By Ximena Camacho, UNSW Sydney, Andrea Schaffer
| PLOS Medicine Verified
Discussion In our population-based cohort study, we found significantly lower risks of falls resulting in ED presentations, hospitalisations, or death among people initiating tapentadol (SR) compared to those of people initiating oxycodone (CR). Tapentadol (SR) was associated with an approximately 40% lower risk of falls within the first 14 days following initiation and a 30% lower risk within 28 days of initiation.
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A Viral Aetiology for Multiple Sclerosis: In Pursuit of Kurtzke’s Dark Horse

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By Ian Sutton, Jennifer Massey, UNSW Sydney
| Multiple Sclerosis and Related Disorders Verified
Get full text access Log in, subscribe or purchase for full access. REFERENCES 1. Link, H. ∙ Huang, Y.M. Oligoclonal bands in multiple sclerosis cerebrospinal fluid: an update on methodology and clinical usefulness J Neuroimmunol. 2006; 180(1-2):17-28 2. McGinley, M.P. ∙ Goldschmidt, C.H. ∙ Rae-Grant, A.D. Diagnosis and Treatment of Multiple Sclerosis: A Review Jama. 2021; 325(8):765-779 3. Kappos, L. ...
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Interfering with innate immunity: type I IFNs and avian influenza susceptibility

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By Stuart G. Tangye, UNSW Sydney, Cindy S. Ma
| EBioMedicine Verified
Type I interferons (IFNs) are central to early antiviral innate immunity, being produced rapidly by diverse cell types to restrict viral replication.1 The importance of type I IFNs in host defence against infections became apparent in studies of mice treated with neutralising antibodies (Ab) against type I IFN, or rendered genetically deficient for the type I IFN receptors (IFNα/βR).
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