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Upendarrao Golla

As seen in: MDPI, BioRxiv, Chemistry World
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Articles

CK2 inhibitor CX-4945 targets EWS-FLI1 signaling network and shows therapeutic efficacy in metastatic mouse models of Ewing Sarcoma

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By Muhammad Daniyal, Rajesh Rajaiah, Upendarrao Golla
| BioRxiv
Abstract Ewing sarcoma (ES) is an aggressive bone tumor that primarily affects children, adolescents, and young adults. EWS-FLI1 oncogenic fusion protein is indispensable for ES tumor survival and progression. Casein kinase II (CK2) is a serine/threonine kinase that plays an essential role in apoptosis, DNA damage repair, and the cell cycle. CK2 is highly expressed in ES and associated with metastatic disease and poor 5-year overall survival.
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From Deworming to Cancer Therapy: Benzimidazoles in Hematological Malignancies

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By Upendarrao Golla, Nyah Shah, Satyam Patel, Stella Talamo
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Role of Immune Cells and Immunotherapy in Multiple Myeloma

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By Vijay Radhakrishnan, Upendarrao Golla, Avinash Kundadka Kudva, Avinash Kundadka
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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