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Urmi Das

As seen in: Nature, BioRxiv, International Journal of Disaster Resilience in the Built Environment
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Articles by Urmi Das

The association of schizophrenia polygenic scores with continuously-hospitalized, treatment-resistant schizophrenia

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By Urmi Das, James J. Crowley, Robert Karlsson, Yi Lu, Michael O’Donovan, James Walters, Michael Didriksen, Patrick Sullivan, Kaarina Kowalec, Richard Josiassen
| Nature Verified
Abstract More than 20% of individuals with schizophrenia show minimal or no response to antipsychotic medications and little is known about genetic contributions to more severe forms of illness. This study sought to explore if cases with continuously-hospitalized, treatment-resistant schizophrenia (CH-TRS) carry a higher burden of common genetic variants compared to less severe forms.
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5-Aza-Cytidine Enhances Terminal Polyadenylation Site Usage for Full-Length Transcripts in Cells

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By Samuel Ogunsola, Ling Liu, Urmi Das, Jiuyong Xie
| BioRxiv
Abstract As an inhibitor of DNA methyltransferases (DNMT) and anti-cancer drug, the many effects of 5-aza-cytidine (5-azaC) on gene expression remains unknown. Here we show that 5-azaC treatment of cultured pituitary tumour cells increases the relative usage of the genomic terminal exons (GTE) across the transcriptome. This effect is largely achieved by switching mRNA polyadenylation (poly(A)) from proximal sites to the GTE, which have a more optimal poly(A) signal consensus motif.
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Epigenetic Control of Adaptive or Homeostatic Splicing of Alternative Exons and Prolactin Gene Expression During Interval-Training Activities of Pituitary Cells

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By Ling Liu, Hai Nguyen, Urmi Das, Samuel Ogunsola
| BioRxiv
Abstract Interval-training activities induce adaptive cellular changes without altering their fundamental identity, but the precise underlying molecular mechanisms are not fully understood. In this study, we demonstrate that interval-training depolarization (ITD) of pituitary cells triggers distinct adaptive or homeostatic splicing responses of alternative exons. This occurs while preserving the steady-state expression of the Prolactin and other hormone genes.
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Volunteer voices of inclusion from IOM Bangladesh

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By Urmi Das, Samara Hamid
| iom.int
11/18/19 By: Samara Hamid and Urmi Das, UN Youth Volunteers In Bangladesh, UN Youth Volunteers bring fresh ideas and additional energy to the International Organization for Migration (IOM), especially in times of emergencies. They provide better access to communities and help engage with local authorities, staff and partners to unveil future possibilities.
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Reduction of cadmium toxicity in wheat through plasma technology

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By Mosiur Rahman, Ahmad Humayan Kabir, Urmi Das, Urmi Sarkar
| PLOS
Loading metrics Open Access Peer-reviewed Research Article Ahmad Humayan Kabir , Md Mosiur Rahman, Urmi Das, Urmi Sarkar, Nepal Chandra Roy, Md Abu Reza, Mamunur Rashid Talukder, Md Alfaz Uddin Ahmad Humayan Kabir, Md Mosiur Rahman, Urmi Das, Urmi Sarkar, Nepal Chandra Roy, Md Abu Reza, Mamunur Rashid Talukder, Md Alfaz Uddin Published: April 1, 2019 https://doi.org/10.1371/journal.pone.0214509 Figures Abstract Cadmium (Cd) contamination in plant-derived food is a big concern.
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