Uzma Akbar

1 Background Primary hyperparathyroidism (PHPT) is characterized by excessive secretion of parathyroid hormone (PTH), leading to hypercalcemia and various systemic manifestations. The classic mnemonic “psychic moans, abdominal groans, renal stones, and painful bones” summarizes the clinical features associated with hypercalcemia, including mood disturbances, gastrointestinal discomfort, nephrolithiasis, and bone pain [1]. Parathyroid adenomas account for approximately 85% of all cases of PHPT.

Congenital hypogonadotropic hypogonadism is a rare reproductive disorder that can be challenging to diagnose. This case underscores the diagnostic complexity of CHH, particularly in the presence of chronic disorders such as celiac disease and Plummer–Vinson syndrome, which can obscure the underlying etiology of delayed puberty.