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Articles by Uzma Bashir
Bioengineering the metabolic network of CAR T cells with GLP-1 and Urolithin A increases persistence and long-term anti-tumor activity
Keywords CAR T cells metabolism GLP-1 peptide Urolithin A autophagy mitophagy mitochondrial health T cell persistence anti-tumor activity Introduction Chimeric antigen receptor (CAR) T cell therapy has revolutionized cancer treatment, demonstrating remarkable efficacy in B cell malignancies.1 CD8+ cytotoxic effector T (Teff) cells are essential for initiating primary adaptive immune responses.2,3 Following antigen clearance, Teff cells can transition into memory T (Tm) cells, forming a...
Offset curves: An application in road simulation
Loading metrics Open Access Peer-reviewed Research Article Citation: Rasheed A, Bashir U (2024) Offset curves: An application in road simulation. PLoS ONE 19(11): e0309698. https://doi.org/10.1371/journal.pone.0309698 Editor: Nasir Ayub, Air University, PAKISTAN Received: May 26, 2024; Accepted: August 18, 2024; Published: November 5, 2024 Copyright: © 2024 Rasheed, Bashir.
A Deep Dive into Integrated Farming System for Doubling Farmers Income in Kashmir
REVOLUTIONIZING AGRICULTURE Nested in the lap of nature, the Kashmir valley is embarking on a journey of agriculture transformation that holds the promise of doubling farmer’s income by adoption of Integrated Farming System (IFS). This innovative approach seeks to harness the synergies between different agricultural activities, presenting a roadmap towards more sustainable and profitable farming approach.
Sequential viral introductions and spread of BA.1 across Pakistan provinces during the Omicron wave - BMC Genomics
Genomic surveillance data from Pakistan has been limited especially, for early pandemic waves of 2020 and 2021. Our study provides insights into the phylogenetic relatedness of different Omicron variants which spread across Pakistan, associating the introduction of the Omicron subvariants with COVID-19 surges in different regions.
Vermicomposting: A viable business opportunity in Kashmir
Vermicomposting: A viable business opportunity in Kashmir The success of vermicomposting business largely depends on the availability of different components Post by Dr. UZMA BASHIR on Monday, July 31, 2023 If you are looking to start your own business, why not consider vermicomposting? It’s a great way to reduce waste and help the environment and can be profitable too.
Comparison of Efficacy of Double Dose Oral Terbinafine versus Itraconazole in the Treatment of Dermatophyte Infections of Skin
Abstract Objective: To compare the efficacy of double-dose oral Terbinafine and Itraconazole in treating dermatophytic infections. Study Design: Randomized controlled trial (ClinicalTrials.gov: NCT04880980). Place and Duration of Study: Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi Pakistan, from Mar 2021 to Mar 2022.
BIO-CONTROL OF BACTERIAL PATHOGENS WITH SOLVENT EXTRACTS OF WEEDS OF AMARANTHACEAE FAMILY
Abstract Biologically active substances have been isolated from weedy plants and investigated against bacterial pathogens for their antimicrobial potential. Medicinal value and biological functions of weeds are being tapped in order to find out novel substances against microorganisms which have developed resistance to current antibiotics and pesticides.
Molecular detection and genetic characterization of human metapneumovirus strains circulating in Islamabad, Pakistan - Scientific Reports
Abstract Lower respiratory illness is one of the leading causes of death among children in low- and high-income countries. Human metapneumovirus (hMPV) is a key contributor to respiratory illnesses commonly reported among children and causes serious clinical complications ranging from mild respiratory infections to severe lower respiratory tract anomalies mainly in the form of bronchiolitis and pneumonia.
ELECTROCARDIOGRAPHIC CHANGES WITH STANDARD DOSE OF MEGLUMINE ANTIMONIATE THERAPY IN CUTANEOUS LEISHMANIASIS
Moizza Tahir Combined Military Hospital Multan/National University of Medical Sciences (NUMS) Pakistan Uzma Bashir Combined Military Hospital Quetta/National University of Medical Sciences (NUMS) Pakistan Najia Ahmed Pakistan Naval Ship Shifa Hospital, Karachi Pakistan Jauhar Mumtaz Ali Medical Centre, Islamabad Pakistan Keywords: Cutaneous leishmaniasis, Electrocardiographic adverse effects, Meglumine antimoniate Abstract Objective: To identify electrocardiographic changes associated with...
ELECTROCARDIOGRAPHIC CHANGES WITH STANDARD DOSE OF MEGLUMINE ANTIMONIATE THERAPY IN CUTANEOUS LEISHMANIASIS
Abstract Objective: To identify electrocardiographic changes associated with parenteral meglumine antimoniate and to estimate frequency of these changes. Study Design: Prospective observational study. Place and Duration of Study: Dermatology department, Combined Military Hospital Quetta and Multan, from Apr 2018 to Feb 2019. Methodology: Total of 87 patients was recruited by consecutive sampling technique. Cases of Leishmaniasis were confirmed by Leishmania donovani bodies in smear or skin biopsy.
Recent advances in combinatorial cancer therapy via multifunctionalized gold nanoparticles
NanomedicineAhead of Print Review , , , , , , Ajmal Khan **Author for correspondence: Tel.: +96 825 446 502; E-mail Address: ajmalkhan@unizwa.edu.om https://orcid.org/0000-0001-7851-6080 Natural & Medical Sciences Research Center, University of Nizwa, P.O. Box 33, Birkat Al Mauz, Nizwa, 616, Sultanate of Oman & Ahmed Al-Harrasi *Author for correspondence: Tel.: +96 825 446 328; E-mail Address: aharrasi@unizwa.edu.om Natural & Medical Sciences Research Center, University of Nizwa, P.O. Box 33,...
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