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Articles by V. Murthy
Editing the Question on Gene Therapy from Can We to When Should We?
Editing the Question on Gene Therapy from Can We to When Should We? This is a continuation of sorts from my prior post here: "Time for a Revision on Gene Editing for Cholesterol?" One of my heroes in science is Linus Pauling, winner of two unshared Nobel Prizes. He was awarded the 1954 Nobel Prize in Chemistry in part for his work on sickle cell anemia, defining it as a molecular disease (https://en.wikipedia.org/wiki/Sickle_Cell_Anemia,_a_Molecular_Disease).
Time for a Revision on Gene Editing for Cholesterol?
One of several highly anticipated clinical trials presented at the 2023 American Heart Association meeting was the heart-1 study (NCT05398029) from Verve Therapeutics. Some leading voices have hailed this a “game-changer” and the dawn of a new era. This was a small study of 10 individuals with heterozygous familial cholesterolemia (HeFH) – a genetic disorder affecting ~1 million Americans which causes elevated low-density lipoproteins (LDL or “bad cholesterol”).
Radiotherapy for Post-Chemotherapy Residual Mass in Advanced Seminoma: A Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography-Based Risk-adapted Approach
Highlights • FDG PET-CT can help to optimise the management of post-chemotherapy residual mass in advanced seminoma. • Risk grouping can be carried out based on uptake in residual mass in PET-CT scan. • Residual mass with SUVmax ≥3 seems to benefit from locoregional radiotherapy. Abstract Aims There is a lack of consensus regarding the management of post-chemotherapy residual mass in classical seminoma.
Safety and Efficacy of Ultra-hypofractionation in Node-positive Prostate Cancer
Highlights • SBRT to the prostate and pelvis in node-positive prostate cancer is safe. • Radiotherapy is effective in controlling common iliac nodal disease. • Prostate dose above 35 Gy and longer duration of ADT may improve outcomes. Abstract Aims The safety and efficacy of stereotactic body radiotherapy (SBRT) in localised prostate cancer are now established through phase III randomised trials.
Adaptive Radiotherapy for Carcinoma of the Urinary Bladder: Long-term Outcomes With Dose Escalation
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig 1 Axial view of on-board megavoltage computed tomography matched with planning computed tomography showing the three planning target volumes (PTVs), with the bladder fitting into the smallest PTV in the first fraction (A) but requiring a larger PTV in the second fraction (B).
Prostate Radiotherapy in India: Evolution, Practice and Challenges in the 21st Century
To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig 1 Geographical distribution of the radiation oncologists responding to the survey. Highlights •A unique patterns of practice survey of prostate radiotherapy in India presented. •There is a trend of early adoption of new technology in India, keeping pace with the West.
Survey on Adaptive Radiotherapy Practice
Publication HistoryPublished online: September 10, 2018Accepted: August 21, 2018; Received in revised form: August 9, 2018; Received: August 4, 2018;
Derring-do on two wheels
Nothing stops the Tornadoes, a daredevil motorbike team of the Army Service Corps. On 500 cc Royal Enfield motorbikes, they do the unthinkable, speeding through fireballs, walls of tube-lights or a bunch of boxes. It seems they defy gravity. The venue was the Manekshaw Parade Grounds in Bengaluru this Independence Day. Last year, they set a world record when 58 men rode a bike for 1.2 km.
Early Results of Extreme Hypofractionation Using Stereotactic Body Radiation Therapy for High-risk, Very High-risk and Node-positive Prostate Cancer
Publication HistoryPublished online: March 20, 2018Accepted: February 19, 2018; Received in revised form: February 7, 2018; Received: December 9, 2017;
INTERNATIONAL JOURNAL OF LIBRARY AND INFORMATION SCIENCE (IJLIS) © IAEME Publication | https://iaeme.com/Home/journal/IJLIS
Articles Archive Subject Area Indexing Aims & Scope Editorial Board For Authors Publication Fees Article Id - IJLIS_05_02_002, Pages : 7-15, Date of Publication : 2016/06/17 Abstract Library and Information Centres from an ordinary individual point of view are only books for reading purpose. But, to any academician, they refer to many other areas which include library resources, library services and library amenities.
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