V. Shane Pankratz

INTRODUCTION Despite improvements in colorectal cancer (CRC) screening rates, over 30% of average-risk, 50-75 year-old adults in the United States are not up to date with CRC screening.1, 2 This percentage is even larger among rural residents, males, those who are closer to age 50, Blacks, Hispanics, and American Indians/Alaska Natives.2-5 Numerous reasons have been identified for low CRC screening rates including health literacy, patient fear, cost concerns, and patient logistics (eg,...

Women with atypical hyperplasia (AH) on breast biopsy have an aggregate increased risk of breast cancer (BC), but existing risk prediction models do not provide accurate individualized estimates of risk in this subset of high-risk women. Here, we used the Mayo benign breast disease cohort to develop and validate a model of BC risk prediction that is specifically for women with AH, which we have designated as AH-BC.

Background  Physical exercise is associated with decreased risk of dementia and Alzheimer disease. Objective  To investigate whether physical exercise is associated with decreased risk of mild cognitive impairment (MCI). Setting  The Mayo Clinic Study of Aging, an ongoing population-based cohort study in Olmsted County, Minnesota. Participants  A total of 1324 subjects without dementia who completed a Physical Exercise Questionnaire.