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Valentine Barassé on Muck Rack

Valentine Barassé

As seen in: Nature, MDPI
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Articles

Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom

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By Valentine Barassé, Laurence Jouvensal, Guillaume Boy, Arnaud Billet
| MDPI
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
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Ant venoms contain vertebrate-selective pain-causing sodium channel toxins - Nature Communications

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By Samuel Robinson, Axel Touchard, Alexander Mueller, Christina I. Schroeder, Valentine Barassé, Andrew Walker, Elsa Bonnafé, Michel Treilhou, Glenn F. King
| Nature Verified
Abstract Stings of certain ant species (Hymenoptera: Formicidae) can cause intense, long-lasting nociception. Here we show that the major contributors to these symptoms are venom peptides that modulate the activity of voltage-gated sodium (NaV) channels, reducing their voltage threshold for activation and inhibiting channel inactivation. These peptide toxins are likely vertebrate-selective, consistent with a primarily defensive function.
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