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Valérie Barbier on Muck Rack

Valérie Barbier

As seen in: Cell Reports Medicine
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Articles

A glucocorticoid spike derails muscle repair to heterotopic ossification after spinal cord injury

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By Hsu-Wen Tseng, Brett C. McWhinney, Selwin G. Samuel, Whitney Fleming, Ingrid Winkler, Marjorie Salga, François Genêt, Sébastien Banzet, Marc J. Ruitenberg, Jean-Pierre Levesque, Kylie A. Alexander, Hong Wa Lao, Dorothée Girard, Valérie Barbier, Jacobus P.J. Ungerer
| Cell Reports Medicine Verified
Keywords Glucocorticoid receptor spinal cord injury neurogenic heterotopic ossification muscle repair inflammation osteoblast fibroadipogenic progenitor dexamethasone mifepristone relacorilant Introduction Effective skeletal muscle repair after injury requires two populations of muscle-resident stem cells working in concert: (1) myogenic stem cells called satellite cells (SCs) that regenerate myoblasts and myofibers1 and (2) mesenchymal progenitor cells (MPCs) called fibro-adipogenic...
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