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Cell-Free DNA Extracted from CSF for the Molecular Diagnosis of Pediatric Embryonal Brain Tumors
4. Discussion Molecular characterization is an integral part of the diagnostic procedures of CNS EBT [3,4]. Nevertheless, in many instances, the quantity of available tumor tissue is limited. Furthermore, modifications in genetic and epigenetic profiles might occur under therapy, with limited possibilities of exploration.
Real-time PCR based on SYBR-Green I fluorescence: An alternative to the TaqMan assay for a relative quantification of gene rearrangements, gene amplifications and micro gene deletions | BMC Biotechnology | Full Text
References de Kok JB, van Balken MR, Roelofs Rwhm, van Aarssen Yawg, Swinkels DW, Gunnewiek Jmtk: Quantification of hTERT mRNA and telomerase activity in bladder washings of patients with recurrent urothelial cell carcinomas. Clin. Chem. 2000, 46: 2003-2007.
Quantitative detection of ALK rearrangements using droplet digital PCR (ddPCR) in liquid biopsies of patients with non-small cell lung cancer (NSCLC)
Quantitative detection of ALK rearrangements using droplet digital PCR (ddPCR) in liquid biopsies of patients with non-small cell lung cancer (NSCLC) Aurélie Swalduz, Laurent Alberti, Valérie Combaret, Sandra Ortiz Cuaran, Sylvie Lantujoul, Juliette Roussel, Agnès Lancon, Séverine Martinez, Véronique Haddad, Dominique Arpin, Jaouali Zouheir, Maurice Pérol, Pierre Saintigny European Respiratory Journal Sep 2016, 48 (suppl 60) OA1782; DOI: 10.1183/13993003.congress-2016.OA1782
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