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Valmira Hoti on Muck Rack

Valmira Hoti

As seen in: BioRxiv
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Articles

Multicellular, fluid flow-inclusive hepatic in vitro models using NANOSTACKS™: a relevant-organ model for drug response prediction

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By Imran Patel, Abdullah Talari, Raffaello Sbordoni, Valmira Hoti
| BioRxiv
Abstract Drug-induced liver injury (DILI) continues to be the leading cause of drug attrition during clinical trials as well as the number one cause of post-market drug withdrawal due to the limited predictive accuracy of preclinical animal and conventional in vitro models. In this study, the NANOSTACKS™ platform was introduced as a novel in vitro tool to build in vivo-relevant organ models for predicting drug responses.
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