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Articles by Van Biesen
Beyond binary AKI classification: development and external validation of a distributional model predicting serum creatinine and urine output trajectories in ICU patients
Study data sources & population We used four large-scale ICU datasets spanning diverse healthcare systems and geographic regions. The training cohort consisted of adult ICU patients from the MIMIC-IV (v3.1) database [15], a publicly available critical care resource containing de-identified records from a single center in Boston, USA.
Addressing the inequity of access to home Dialysis in Europe: recommendations for action informed by an international consensus exercise - BMC Nephrology
References Davies SJ. The future of Peritoneal Dialysis. Clinical Kidney Journal [Internet] 2024;17:ii9–ii18. Available from: https://doi.org/10.1093/ckj/sfae277 Vanholder R, Bach D, Davies S, Finne P, Mitra S. Proactively boosting home dialysis adoption in Europe. Nephrology, dialysis, transplantation: official publication of the European Dialysis and transplant association. European Renal Association; 2024. Boerstra BA, Boenink R, Astley ME et al. The ERA Registry Annual Report 2021: a summary.
A Population Pharmacokinetic Analysis for Piperacillin/Tazobactam in Patients with End-Stage Kidney Disease Undergoing Intermittent Haemodialysis: Extension of a General-Purpose Model | Clinical Pharmacokinetics
Abstract End-stage kidney disease (ESKD) patients undergoing haemodialysis (HD) require a dosing regimen that balances the low endogenous clearance with the additional dialyser clearance. This study aimed to expand a previously proposed general-purpose pharmacokinetic model for piperacillin/tazobactam with a new population of ESKD patients undergoing intermittent high-flux haemodialysis.
Comparison and Optimization of DNA Extraction Methods for Human DNA from Dried Blood Spot Samples
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Ethical considerations on the use of big Data and Artificial Intelligence in kidney research from the ERA ethics committee
In the current paper, we will focus on requirements to ensure big data can advance the outcomes of our patients suffering from kidney disease. The associated ethical question is whether and how we as a nephrology community can and should encourage the collection of big data of our patients. We identify some ethical reflections on the use of big data, and their importance and relevance.
Towards a better uptake of home dialysis in Europe: understanding the present and looking to the future
Europe is far from a homogenous region, with substantial differences in economies, geography, population demographics, language, culture and organization of healthcare delivery. Although there is some political and economic cohesion with 28 countries being members of the European Union, organization of healthcare delivery remains mostly individual country dependent. There are therefore inevitable differences in the organization and delivery of healthcare between countries.
Scoping review of dual-task interference in individuals with intellectual disability
Roi Charles Pineda1* Ralf Th Krampe2 Yves Vanlandewijck1,3 Debbie Van Biesen1,4 1Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium 2Brain and Cognition Group, Faculty of Psychology and Educational Sciences, KU Leuven, Leuven, Belgium 3Department of Physiology, Swedish School of Sport and Health Sciences, Stockholm, Sweden 4Virtus Academy, Virtus World Intellectual Impairment Sport, Sheffield, United Kingdom Dual-task paradigms can provide insights on the structures and...
“The show must go on”: How Paralympic athletes safeguarded their mental well-being and motivation to train for the postponed Tokyo 2020 games
Introduction Across the world, corona measures were taken to contain the spreading of the COVID-19 virus (e.g., lockdown, wearing face masks, keeping social distance, etc.).
“Many roads lead to Rome and the Artificial Intelligence only shows me one road”: an interview study on physician attitudes regarding the implementation of computerised clinical decision support systems | BMC Medical Ethics | Full Text
Our findings are based on an analysis of the audio recordings of twenty-four interviews. The respondents all worked at Ghent University Hospital. Fifteen respondents identified as female and all were at different stages of their career. Based on our analysis we identified three overarching themes, which can be further divided into smaller themes and subthemes: (1) Perceived role of the AI; (2) Perceived role of the physician; and (3) Concerns regarding AI.
Sustainable Development Goals relevant to kidney health: an update on progress - Nature Reviews Nephrology
Abstract Globally, more than 5 million people die annually from lack of access to critical treatments for kidney disease — by 2040, chronic kidney disease is projected to be the fifth leading cause of death worldwide. Kidney diseases are particularly challenging to tackle because they are pathologically diverse and are often asymptomatic. As such, kidney disease is often diagnosed late, and the global burden of kidney disease continues to be underappreciated.
Development of an International Standard Set of Value-Based Outcome Measures for Patients With Chronic Kidney Disease: A Report of the International Consortium for Health Outcomes Measurement (ICHOM) CKD Working Group
Verberne, WR; Das-Gupta, Z; Allegretti, AS; Bart, HAJ; van Biesen, W; García-García, G; Gibbons, E; ...
Cardiac surgery-associated acute kidney injury: risk factors, pathophysiology and treatment
Abstract Cardiac surgery-associated acute kidney injury (CSA-AKI) is the most common clinically important complication in adult patients undergoing open heart surgery, and is associated with increased mortality and morbidity. In patients in intensive care units, CSA-AKI is the second most common type of AKI after septic AKI. In this Review, we explore the definition of CSA-AKI, discuss its epidemiology and identify its risk factors.
Reducing the costs of chronic kidney disease while delivering quality health care: a call to action
Abstract The treatment of chronic kidney disease (CKD) and of end-stage renal disease (ESRD) imposes substantial societal costs. Expenditure is highest for renal replacement therapy (RRT), especially in-hospital haemodialysis. Redirection towards less expensive forms of RRT (peritoneal dialysis, home haemodialysis) or kidney transplantation should decrease financial pressure.
Changes in the worldwide epidemiology of peritoneal dialysis
Abstract As the global burden of chronic kidney disease continues to increase, so does the need for a cost-effective renal replacement therapy. In many countries, patient outcomes with peritoneal dialysis are comparable to or better than those with haemodialysis, and peritoneal dialysis is also more cost-effective. These benefits have not, however, always led to increased utilization of peritoneal dialysis.
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