Van Thuy Duong

1 Introduction Decellularized extracellular matrices (dECM), a fibrillar network of acellular proteins and glycosaminoglycans (GAG), have been increasingly used to construct bioactive scaffolds for promoting tissue regeneration.[1] dECM contains abundant bioactive ligands, limited residual growth factors, and micro/nanofiber structures, all benefiting cell attachment and morphogenesis.[2] For example, decellularized small intestine submucosa (dSIS) has a long history in biomedical...

Abstract Volumetric skeletal muscle injuries are prevalent, highlighting the imperative need for scaffolds to facilitate the healing process of such wounds. Human skeletal muscle is composed of multiple fascicles, which are parallel bundles of muscle fibres surrounded by a layer of connective tissue that contains blood vessels and nerves. Replicating these structures presents a considerable challenge.