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Vanessa D Silbar on Muck Rack

Vanessa D Silbar

As seen in: BioRxiv
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Articles

SICKO: Systematic Imaging of Caenorhabtidis Killing Organisms

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By Luis Espejo, Samuel Armbrust Freitas, Vanessa D Silbar
| BioRxiv
Abstract Caenorhabditis elegans are an important model system for host-microbe research due to the ability to rapidly quantify the influence of microbial exposure on whole-organism survival and rapidly quantify microbial load. To date, the majority of host-pathogen interaction studies rely on host group survival and cross-sectional examination of infection severity.
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The Emerging Role of 3-Hydroxyanthranilic Acid on C. elegans Aging Immune Function

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By Luis Espejo, Destiny D DeNicola, Vanessa D Silbar
| BioRxiv
Abstract 3-hydroxyanthranilic acid (3HAA) is considered to be a fleeting metabolic intermediate along tryptophan catabolism through the kynurenine pathway. 3HAA and the rest of the kynurenine pathway have been linked to immune response in mammals yet whether it is detrimental or advantageous is a point of contention. Recently we have shown that accumulation of this metabolite, either through supplementation or prevention of its degradation, extends healthy lifespan in C.
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