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Vani Srinivasan on Muck Rack

Vani Srinivasan

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Articles

Quantitative modulation of a spatial enhancer through the biophysical properties of a transcription factor binding site

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By Janni Yuval, Xintao Li, Juha Aalto, Conrad Fallon, Liucong Ling, Brendon Cooper, Stefano Ceolin, Tsu-Pei Chiu, Raktim Mitra, Bettina Mühling, William J Glassford, Vani Srinivasan, Ayse Damla Durmaz, Daniel Veselinovic, Mahek Kothari, Athanasios Panagiotis Fylaktakis, Judith F. Kribelbau
| Science Magazine Verified
Abstract Fine-tuning of gene expression by transcription factors (TFs) is essential for normal development, but how TF binding is converted into precise expression levels is poorly understood. We used a Drosophila enhancer responding to the TF Distal-less (Dll) to investigate this relationship.
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