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Vanisri Raviraj on Muck Rack

Vanisri Raviraj

As seen in: British Journal of Cancer
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Articles

Self-organized centripetal movement of corneal epithelium in the absence of external cues

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By Alex Richardson, Erwin P. Lobo, Naomi C. Delic, Vanisri Raviraj
| British Journal of Cancer Verified
To address the mechanism of centripetal migration in the cornea, we developed a free-lattice mathematical simulation model (described in Methods and in the Overview, Design concepts, Details (ODD) protocol in Supplementary Methods). The cornea is represented as a circular collection of polygonal cells. Its rim forms a niche that supports LESCs, which have fixed locations (Fig. 1a). The lineage path that LESCs follow is essentially that described for corneal epithelia by Lehrer and colleagues6.
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